Motrin (ibuprofen) is used to treat mild to moderate pain. Learn side effects, dosage, drug interactions, warnings, patient labeling, reviews, and more. Motrin IB is a nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen works by reducing hormones that cause inflammation and pain in the body. Motrin IB is used to reduce fever and treat pain or inflammation caused by many conditions such as headache, toothache, back pain, arthritis, menstrual cramps, or minor injury. For relief from muscle aches, fevers, cramps, & more, MOTRIN® is pain relief you can count on. Learn how MOTRIN® can help relieve pain for you & your child. What Is MOTRIN®? Learn more about ibuprofen, the active ingredient in MOTRIN®, and how this NSAID can help reduce fever and relieve pain for all members of your family. It is available under a number of brand names including Advil, Brufen, Motrin, and Nurofen. [7][13] Ibuprofen was first sold in 1969 in the United Kingdom and in 1974 in the United States. [7][12] It is on the World Health Organization's List of Essential Medicines. [14] TIME-Cap Labs Ibuprofen 200mg Pain Reliever & Fever Reducer, 500 Tablets | Temporarily Relieves Minor Aches & Pains due to Headache, Toothache, Backache, Muscular Aches & Menstrual Cramps | For Adults. Motrin Children's Dye-Free Chewable Tablets with Ibuprofen, Kids' Fever Reducer & Pain Reliever for Sore Throat, Fever, Toothache & Pain Relief, Grape Flavor, 24 Ct Motrin (ibuprofen) is a widely used over-the-counter pain reliever and anti-inflammatory medication. Dosage varies by age, weight, and medical condition, with specific guidelines for adults and children. Ibuprofen (Advil, Motrin) treats minor aches and pains caused by the common cold, headaches, toothaches, back or muscle aches. Overview: Ibuprofen is used to reduce fever, pain, and swelling. It works by blocking certain substances in the body that cause pain, inflammation, and fever. Common side effects include stomach.